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Pyknosis

In today's world, Pyknosis is a topic that has sparked great interest and debate in different areas. Its relevance and impact are undeniable, and its influence extends to a wide range of aspects of daily life. As time progresses, Pyknosis continues to be the object of analysis, reflection and study, since its importance is not limited to a single area, but crosses borders and affects people of different cultures, ages and social conditions. In this article, we will explore this topic in depth, analyzing its different perspectives and consequences, in order to better understand its scope and meaning in today's society.

Apoptosis
Morphological characteristics of pyknosis and other forms of nuclear destruction

Pyknosis, or karyopyknosis, is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis. It is followed by karyorrhexis, or fragmentation of the nucleus. Pyknosis (from Ancient Greek πυκνός meaning "thick, closed or condensed") is also observed in the maturation of erythrocytes (a red blood cell) and the neutrophil (a type of white blood cell). The maturing metarubricyte (a stage in RBC maturation) will condense its nucleus before expelling it to become a reticulocyte. The maturing neutrophil will condense its nucleus into several connected lobes that stay in the cell until the end of its cell life.

Pyknotic nuclei are often found in the zona reticularis of the adrenal gland. They are also found in the keratinocytes of the outermost layer in parakeratinised epithelium.

See also

References

  1. ^ Kumar V, Abbas A, Nelson F, Mitchell R (2007). Robbins Basic Pathology (8th ed.). pp. 6, 9–10 (table 1-1).
  2. ^ Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH, et al. (January 2009). "Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009". Cell Death and Differentiation. 16 (1): 3–11. doi:10.1038/cdd.2008.150. PMC 2744427. PMID 18846107.
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