Wiki90

 Wiki90.com

Wiki90: 90s Style Encyclopedia on the Web

Dive into Wiki90, the online encyclopedia that captures the spirit of the '90s. With a design reminiscent of the early days of the Internet and a rich repository of knowledge, Wiki90 is your portal to nostalgia and learning. Discover and relive iconic moments from an unforgettable era online!

Squamous metaplasia

In today's world, Squamous metaplasia has become an increasingly relevant topic of general interest. With the advancement of technology and changes in society, Squamous metaplasia has not only captured the attention of specialists in the field, but also of the general public. This is why it is crucial to delve into the most relevant aspects of Squamous metaplasia, so that its impact can be understood in different areas and contexts. In this article, we will delve into the analysis of Squamous metaplasia, exploring its different dimensions and its implications today. From its origins to its current evolution, we'll take a look at how Squamous metaplasia has shaped the way we understand the world around us.

Micrograph showing squamous metaplasia (centre of image) in an atypical polypoid adenomyoma. H&E stain

Squamous metaplasia is a benign non-cancerous change (metaplasia) of surfacing lining cells (epithelium) to a squamous morphology.

Location

Common sites for squamous metaplasia include the bladder and cervix. Smokers often exhibit squamous metaplasia in the linings of their airways. These changes don't signify a specific disease, but rather usually represent the body's response to stress or irritation. Vitamin A deficiency or overdose can also lead to squamous metaplasia.

Uterine cervix

In regard to the cervix, squamous metaplasia can sometimes be found in the endocervix, as it is composed of simple columnar epithelium, whereas the ectocervix is composed of stratified squamous non-keratinized epithelium.

Significance

Squamous metaplasia may be seen in the context of benign lesions (e.g., atypical polypoid adenomyoma), chronic irritation, or cancer (e.g., endometrioid endometrial carcinoma), as well as pleomorphic adenoma.

  • Cytology of squamous metaplasia of the cervix, with typical features. Pap stain.
    Cytology of squamous metaplasia of the cervix, with typical features. Pap stain.
  • Endometrial adenocarcinoma (carcinoma at left in image) with squamous differentiation evidenced as necrotic “ghost cells” of keratinocytes at right in image, leaving pink keratin as well as clear spaces at the prior locations of the cell nuclei.
    Endometrial adenocarcinoma (carcinoma at left in image) with squamous differentiation evidenced as necrotic “ghost cells” of keratinocytes at right in image, leaving pink keratin as well as clear spaces at the prior locations of the cell nuclei.

See also

References

  1. ^ Goralczyk, R (2009). "β-Carotene and Lung Cancer in Smokers: Review of Hypotheses and Status of Research". Nutrition and Cancer. 61 (6): 767–774. doi:10.1080/01635580903285155. PMID 20155614.
  2. ^ Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; & Mitchell, Richard N. (2007) Robbins Basic Pathology (8th ed.). Saunders Elsevier. pp. 716-720 ISBN 978-1-4160-2973-1
Wikious
Boobota
Sagapedia